![]() ![]() Women with late-onset preeclampsia had higher mean arterial blood pressure levels at 37 weeks of gestation, than the normotensive groups and higher increases in this marker between 20 and 37 weeks of gestation. Women with early-onset preeclampsia had higher mean arterial blood pressure levels at 20 weeks of gestation, compared to the normotensive group. Of the 1373 participants enrolled, complete data were available for 1165. The accuracy of mean arterial blood pressure in the prediction of preeclampsia was determined by ROC curves. Increments in mean arterial blood pressure between 20 and 27 weeks and 20 and 37 weeks of gestation were also calculated for the three groups studied. Groups with early-onset preeclampsia, late-onset preeclampsia and normotension were compared. Mean arterial blood pressure was evaluated at three different time periods during pregnancy. This was a cohort approach to a secondary analysis of the Preterm SAMBA study. The goal of this study was to assess mean arterial blood pressure (MAP) levels at 19–21, 27–29 and 37–39 weeks of gestation and performance of screening by MAP for the prediction of preeclampsia in a Brazilian cohort of healthy nulliparous pregnant women. The vast majority of prospective studies in large general obstetric populations have failed in the purpose of obtain a useful and effective model of prediction, sometimes based on complex tools unavaible in areas where the incidence of preeclampsia is the highest. Prediction of preeclampsia is a challenge to overcome. ![]()
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